Sentence examples for varied efficacy from inspiring English sources

Another important factor to consider in drug design is the conformational flexibility of GPCRs since it has been shown that small‐molecule ligands of varied efficacy stabilize different receptor conformations leading to functional selectivity of ligands.

Using an individual-based, epidemiological simulation model, gonococcal prevalence was simulated in a heterosexual population of 100,000 individuals after the introduction of vaccines with varied efficacy (10 100%) and duration of protection (2.5 20 years).

should not be lumped together because of their varied efficacy.

We assumed 60% efficacy of circumcision in reducing heterosexually-acquired HIV over a lifetime, and varied efficacy in sensitivity analyses.

Different GBM antigens offer varied efficacy of DC-based vaccination.

As single agents, they induce apoptosis in lymphomas and small cell lung carcinomas with varied efficacy.

We varied each of these three potential mechanisms independently to vary efficacy levels from 50%to90%0%.

We assessed the effectiveness of 1,000 postexposure vaccines that varied in efficacy from 50%to90%0%; vaccine efficacy was defined by the degree of reduction in the disease progression rate of latently infected persons.

15 The efficacy of the UK comparator regimen may have been underestimated; therefore, we varied the efficacy in sensitivity analyses and found that the efficacy would have to increase by 16% for the ICER to reach £30,000/QALY.

In animal models, diverse BCG sub-strains exhibit varied protective efficacy against experimental infection with M. tuberculosis and induced qualitatively different immune responses [37].

First, we varied the efficacy of first-line ART when resumed after ART interruption, reflecting potential interruption-associated drug resistance.