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To evaluate GDBP's robustness to lighting variations, we compared the histograms of six representations extracted from the two images of the same eye with different lighting (see Figure 3).
To evaluate any intra-species variations, we compared the dif-related sequences in the 21 multi-strain dif+ species (Table S1) and calculated the degree of variability at each nucleotide position in the dif locus (Figure 1B).
To exclude the possibility that increased proliferation of cells that stably express BAD was due to clonal variations, we compared proliferation in cells transiently transfected with either BAD or empty vector.
To verify that the results obtained were not due to clonal or line variations, we compared the results obtained in cardiomyocytes differentiated from two different clones of the main hiPSC line studied (hIH1 - clones 1&2 derived independently from the human fibroblasts) as well as from an additional well-characterized hiPSC line (hfib2-5) derived using the traditional 4-factors method [8], [17].
For sample-sample (biological) variations, we compared pooled samples (samples A, B and C) prepared using the Bioo Scientific and NEB kits.
To eliminate annual variations, we compared the incidence over the period 1993 96 with the incidence over the period 2001 05.
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To investigate the source of this variation, we compared the array call rate to the mismatch rate.
Rate variation was measured as maximum/minimum estimated rate; to evaluate the causes of observed rate variation, we compared this result to the variation expected due to the stochastic substitution process.
First, to assess the range of tissue-specific isoform variation, we compared murine ataxin-3 expression in various tissues including forebrain, midbrain plus hindbrain, heart, kidney, liver, skeletal muscle, and spleen in wildtype (Q6) versus Atxn3 knockout animals (Figure 2B).
To test for the presence of such variation, we compared the sequences of sex-related locus genes for the presence of multiple paralogs, and also characterized the putative sex-related locus from three distinct species and multiple strains in the genus Encephalitozoon.
In order to assess whether the genetic heterogeneity observed in cell lines was accompanied by functional variation, we compared clones from LM-MEL-62 to the parental line.
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CEO of Professional Science Editing for Scientists @ prosciediting.com