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Population studies designed to determine the links between genotype and phenotype have uncovered numerous genetic variations that influence function of the immune system.
Because mutts are a hodgepodge of DNA from different breeds, finding particular genetic variations that influence the same traits in these dogs will provide more concrete evidence of their effects.
Researchers looked at genetic variations that influence the production and activity of two key neurochemicals -- dopamine and serotonin -- which play important roles in a variety of things, including mood, heart health, metabolism, movement and motivation.
Genetic association studies provide a potentially powerful tool for identifying genetic variations that influence susceptibility to common diseases.
Pharmacogenomics, closely associated with pharmacogenetics, is the study of genetic variations that influence the response of individuals to drug treatment [1,2].
Furthermore, the authors identified two cases of co-inheritance of several independent genetic variations that influence the abundance of related proteins in a biologically coherent manner.
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There are important gene variants, to some extent associated with ethnic variation, that influence metabolic rate.
Sequencing and exome-chip technologies have motivated development of novel statistical tests to identify rare genetic variation that influences complex diseases.
One possible explanation for variation in response to chemotherapy is genetic variation that influences gene expression and, ultimately, impacts variation in drug response phenotypes [6] [8].
Some genes have been implicated in the biological pathways that influence hair graying in mice [38] but genetic variation that influences the prevalence of human graying has yet to be identified.
These stabilize signaling levels in the face of temperature variation that influences ligand-induced receptor activation.
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