Sentence examples for variations that function from inspiring English sources

It is particularly important in some protozoans (eg., trypanosomes, Plasmodium) where it plays a major role in regulating genes involved in antigenic variations that function in evading host immunological defense mechanisms [63], [64].

Population studies designed to determine the links between genotype and phenotype have uncovered numerous genetic variations that influence function of the immune system.

Thus, our SOM analysis correctly reflected the phenotypic metabolic variations that indicate functioning biochemical pathways, and therefore represents a phenotypic linkage map (PLM).

Furthermore, for any given function and at any given chronologic age, there is large variation in that function among individuals.

Sequence variations that affect gene function and cause phenotypic variation represent functional (also known as perfect or diagnostic) markers [ 59, 60].

DNA repair must be accurate to preserve genome stability for long-term cellular viability; genetic instability is characteristic of cancer cells, and may be due, at least in part, to mutations or variation in genes that function to ensure DNA integrity [ 37].

The small size of the regions identified here will facilitate the search for causal genetic variations that affect gene functions.

In some cases, these modifications still allow the gene to produce a functional protein but with slight variations that may affect its function.

Given the important predictive role of SLC22A1 expression, some investigators have focused on gene variations that may affect hOCT1 function [ 35, 36].

Thus, structural variations that impact on the functions of these proteins have potential to modify broad transcriptional activities and metabolism.

This conclusion is based on the assumption that currently available bioinformatic tools can accurately distinguish variations that will change the protein function and ultimately result in a behavioral phenotype.