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Because of the nature of the problem being solved, we mainly focus on variations that define the currently known CYP2D6 alleles.
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Such information is also important to establish the foundation for mining non-coding sequence variation that defines novel alleles and epialleles across the enormous phenotypic diversity represented in rice germplasm.
However, this approach is limited in its ability to yield complete genome sequences as well as the fine-scale genetic variation that defines population substructures within these communities.
The genome project has made biologists appreciate the importance of "single nucleotide polymorphism" (SNP)—minor variations in DNA that define differences among people, predispose a person to disease, and influence a patient's response to a drug.
Although this approach to understanding diseases is essential, research at this level mutes the variation and interconnectedness that define the true underlying medical mechanisms [ 7].
To make the results comprehensive, dimensionless analysis is used, and a large variation limit of parameters that define the crack geometry is considered.
There is considerably less variation in the motifs that define B haplotypes, the most diverse being Cen-B2 with six allele combinations.
Interestingly, when comparing the core/pan-genome ratio; we found a clear discontinuous variation that can define a new species.
Tower tells a powerful tale of fight, flight, and the many variations of the two that defined individuals' experiences of that day, begging that dreaded question of its audience: What would you have done?
Fashioning a darker and more introspective variation on the role that defined Pat Morita, Mr. Han was a rare chance to see Jackie Chan in a straight-up dramatic role in an American film.
We note: (1) the dependence of the thresholds on the mean and standard deviation through the coefficient of variation (CV); and, (2) that defining thresholds based on absolute relative changes results in thresholds which require larger %-decreases for statistical significance (but smaller %-increases).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com