Sentence examples for variations that alter from inspiring English sources

The existence of genetic variations that alter risk of developing both obesity and prostate cancer could constitute evidence in favour of a causal link between the two diseases.

However, variations that alter the protein sequence occur in very few genes.

Single nucleotide polymorphisms (SNPs): genetic variations that alter a single nucleotide in the genome.

Genetic variations that alter this site of action might account for this and other reported cases of local anesthetic "resistance" or failure.

Second, we only considered gene variations that altered the open reading frame of the encoded protein (nonsynonymous amino acid changes, frameshifts, truncations, nonframeshifting indels, splice site alterations and stop codon losses).

Although correlations between the differentiation capacity of hPSCs and these genetic variations have not been systematically examined, it is feasible that cellular pluripotency and differentiation propensity may differ in different hPSC lines partially due to intrinsic genetic variation that alters cell signaling mediated by protein phosphorylation.

These water scarcity issues in the region are intensified by climate variations and changes that alter the hydrologic cycle and many of the countries are dependent mainly on groundwater, desalination and treated wastewater (Amin et al. 2013; Chowdhury and Champagne 2006).

The purpose of this study was to evaluate the impact of genomic variations on different mechanisms that alter drug efficacy.

Variations in DNA sequence that alter promoter activity also correlate with the predisposition of promoters to hypermethylation.

The highly cooperative nature of IRE1 (and likely PERK) activation is poised to respond to subtle variation in the factors that alter the tendency of TM proteins to dimerize.

Alternatively (reverse causality), variations in the fetal genome that alter fetal growth also could alter maternal appetite and metabolism (for example a larger fetus and placenta may stimulate greater maternal food intake), and this could lead to insulin resistance and glucose intolerance during pregnancy and a higher diabetes risk later (27, 28).