Previous studies have shown a wide variation of reported emission estimates: the results of this study are benchmarked with data from those studies.
Fig. 2 illustrates this wide variation of reported incidence rates.
On the other hand, the within-study variation of reported non-compartment PK parameters is moderate, CV = 27%.
Variation of reported percentages is most likely based on selection of cases (benign and malignant as well as morphologic subtypes), technical factors and subjective interpretation.
For the midazolam/ketoconazole system, a mixed inhibition model coupled with independent binding of the drug, inhibitor, and metabolite is sufficient to explain the variation of reported Vmax, Km, and inhibitor constants across a range of reported studies.
One reason for the variation of reported inhibition types and the values of inhibition constants is that complex cellulase mixtures are often used instead of purified cellulase components in experiments.
After decades of study, there is still a general need to establish concurrent methods for the different processing steps of platelets because the wide variation of reported protocols for platelet preparation leads to different biological responses and incomparable data.
The case-finding algorithm to identify HF patients with depression and anxiety obtained from the sub-study could be recommended for further observational and intervention studies in HF patients and is likely to reduce the huge variation of reported prevalence rates.
The nighttime behavior (Fig. 4(c)) indicates somewhat "wave-like" pattern parallel to longitudinal behavior presented by Liu et al. (2010) and seasonal variations of Bo reported by Chen et al. (2006) and Zhang et al. (2008).
For ER staining, cells were transfected with an ER-targeted fluorophore, ER-mCherry, produced using variations of previously reported methods [59], [60].
