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The cytotoxic potency of 4-alkylamino-5-nitroquinoline drugs in AA8 cell cultures is enhanced up to 60-fold under hypoxia, with wide variations in selectivity for hypoxic cells observed for different members of this series.
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As the initial structural match to, and the subsequent differential host relaxation around, the pX and mX guests are both involved in selection between them, variation in selectivity with lanthanide size across the family of [Ln HTCPB)] phases (accessible for Ln=La Sm) might be expected.
This review is focused on the development of chemosensors containing NH-binding sites for application in anion sensing and discusses the variation in selectivity as a consequence of structural modification.
In contrast to the MTO reaction, there was little variation in selectivity, stability or activity shown when the temperature was changed from 350 to 500 °C.
In contrast, yeast Fps1p did not exhibit significant MAs III) conductivity, demonstrating that aquaglyceroporins have a wide variation in selectivity for arsenicals.
These agree with the experimental observations and provide an explanation for variations in reaction selectivity.
Figures 6 and 7 demonstrate the variations in the selectivity of diesel against TR, TOS, and H2/CO ratio inlet gas.
To gain additional insight into variations in substrate selectivity, we have analyzed two SDC-like enzymes from Medicago truncatula and Cicer arietinum.
In most animal species examined different MT isoforms show poor or no appreciable differentiation and specialization in their functions and metal-binding preferences [ 7, 8], although variations in metal selectivity between MT domains exist in some cases [ 9- 11].
By using calcium imaging to visualize dendritic activation during visual motion in various directions, we were able to obtain a direct view at the local variations in directional selectivity of the dendrites of individual fly LPTCs.
However, rather than simply integrating inputs in a purely retinotopic way, some LPTCs also exhibit local variations in direction selectivity that are the result of indirect non-retinotopic inputs, which converge via extended synapses from the contralateral brain hemisphere.
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