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In the context of continuous pharmaceutical oral dosage manufacturing, a control system is essential to ensure that the critical quality attributes (CQAs) are maintained within the regulatory constraints by mitigating variations generated in upstream operations.
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Conversely, levels of genetic variation generated in the mosquito were relatively high and generally consistent among lineages (Figs. 2 and 3).
We analyzed the applications with respect to: the adaptation process; the "precision differential" which we define as the variation generated in the model between the degree of spatial variation within the spatial distribution of ES and what the model captures; the stakeholders' opinions on the usefulness of models.
1 More recently, it has helped recreate human migration patterns, 2, 3 and the huge phenotypic variation generated in domesticated species have been used to map causal genes and the mutations underlying a variety of trait types.
Finally, we show there are no apparent hot- or cold-spots within the genome for variations generated via either in vitro culture or chemical mutagenesis.
A visual representation of the alignment and regions of interspecific variation was generated in mVISTA [ 49].
To this end I exploit variation generated by volatility in the U.S. economy between 1976 and 1996.
This suggests that gene content variation (that is generated in the clonal species almost exclusively through gene loss) occurs in a clocklike manner along changes in gene sequences.
Importantly, because fragments of expressed genes are resequenced many times in RNA-seq studies, data on genetic variation are also generated in the process.
Rather, underlying "background" genetic variation is quickly generated in our initially clonal populations and plays a crucial role in determining the fate of each individual beneficial mutation in the evolving population.
The extent of variation in gene content generated in the trajectory is captured by the peak variation (1 − x0 − x n ) during the dynamics.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com