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To minimize individual variations, expression of all examined genes at Weeks 8 and 12 were normalized to the values at baseline prior to identification of differentially expressed genes and pathways.
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This confirmed that the disease phenotype strongly influenced the variations of expression of the 2959 genes differentially expressed between the three patient groups, reinforcing the biological significance of this set of genes (Table S2).
Assessment of seasonal variations in expression of brain neuropeptide mRNA is complicated by concurrent circadian variations.
While tumour heterogeneity also explains individual variations in treatment response, a monitoring approach based only on a single marker is sensitive to variations in expression of that marker.
They also used GWAS to identify loci associated with variation in expression of testis-expressed genes.
In other species studied, genomic sequence variations prevent expression of the EGF1 domain and only the EGF2 domain is present (Fülöp et al. [1996]).
Figure 5 shows variations of expression of 46 ion-channel subunits in the ventricles of 10 week-old Scn5a+/− mice relative to their expression in WT littermates.
We used SAM to evaluate the significance of variations in expression of each gene [ 21].
Little is known however, about the details of the variations in expression of different Syts.
Genetic variations controlling expression of FMO segregated with atherosclerosis in hyperlipidaemic mice.
We did not observe any difference between female and male patients used in our study for the variations of expression of PLA2G3, PLA2G2D and PLA2G5 (data not shown).
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