Sentence examples for variations at single from inspiring English sources

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Importantly, quantitating variations at single sites is not always possible and 30% of detected peptides carry multiple phosphorylations, 5a for which measuring contribution of each site to the total variation of phosphopeptide may not be feasible.

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Few previous studies have employed such large collections of intraspecific sequence variants in order to analyze patterns of adaptive molecular variation at single genes [22].

Next-generation sequencing technologies now present the possibility of determining genome-wide genetic variation at single base-pair resolution.

Variations observed at single cell level indicated insufficient M2-transactivator levels for a subset of the transduced cells.

Single nucleotide polymorphisms (SNPs) are variations at a single base pair (fig 1 ) and are the most common type of human sequence variation, occurring about every 500-1000 DNA base pairs.

Some of them are mutations located within endonuclease restriction sites, others are single nucleotide polymorphisms (SNPs: DNA variations at a single nucleotide) or consist of insertions or deletions of larger fragments as detected by polymerase chain reaction technique (PCR) [ 9].

To date, surveys of mitochondrial coding regions in corals [ 25, 27, 28] have found little or no variation, but these studies have included just a few individuals (≤ 8) and a few localities (≤ 3), and have not been accompanied by surveys of variation at single-copy nuclear markers.

It has now become more common in molecular genetic studies to perform association analysis covering the whole genome by considering associations with a large array of single nucleotide polymorphisms (SNPs) (i.e., variations at a single nucleotide site that differ between members of a species; McCarthy et al. 2008).

Interphase FISH technique is known as a powerful approach to assess intercellular chromosome variations at the single cell level [3], [4].

Such analysis would allow us to capture spatial variations at a single time stage, as well as varying relationships between genes across time.

We analyzed spatial genetic variation in wild barley populations collected rather recently, exploring sequence variations at seven single-copy nuclear loci, and inferred the relationships among these populations and toward the genepool of the crop.

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