Finally: at least I do not realize that "much of this variation is adaptive".
Nevertheless, the fixation of different LDH variants in D. pulex and D. pulicaria in different aquatic habitats, despite the fact that they share polymorphisms at other allozyme loci [ 19- 21], suggests the possibility that Ldh variation is adaptive.
Understanding the maintenance of genetic diversity requires identification of situations in which such genetic variation is adaptive; this problem can be approached from both ecological and genomic perspectives [ 32].
However, the radical reappraisal of the nature of genomic variation and the realization that much of this variation is adaptive, thus apparently eliminating the conflict between the Lamarckian and Darwinian scenarios, is a veritable, although underappreciated paradigm shift in modern biology.
This, coupled with the strong association between LdhA genotype and habitat, suggests that experimental studies would be useful to determine if there is a link between the protein variants and differences in enzymatic function, which could then be evaluated for their effects on fitness to test the hypothesis that LDHA variation is adaptive.
In a similar way, Vernot et al. [ 10] have found hundreds of variations that are adaptive.
Jablonka also argues that the requirement for high fidelity of replication (e.g., Sterelny 2001) is not as necessary for inheritance systems that employ filtering mechanisms that ensure that transmitted variations are typically adaptive (Jablonka 2002).
If the underlying regulatory variations tagged by eQTLs are adaptive, eQTLs in region of low recombination are expected to show stronger footprint of adaptation.
Since these genes have significantly high K A values within populations, between populations, or both, their amino acid variations may be adaptive.
Switching operations are proposed to achieve these protocols that are adaptive with the variation of the wireless channel.
