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If risk E-1 haplotypes have an adaptive advantage in certain Sub-Saharan populations, recombination could be a quick and efficient way to provide novel and neutral genetic variation to replace previously selected sequences in populations moving to new environments.
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To achieve more rapid convergence, a sub-problem optimal solution updating direction-guided variation strategy is developed to replace the original variation strategy of the RVEA.
One example being copy number variation (CNV) analysis suited to replace traditional MLPA (multiplex ligation-dependent probe amplification) analysis.
In the first part, of this paper it is pointed out that for certain applications of the stochastic calculus of variations it is useful to replace the classical domain of definition the Wiener space with a general probability space in which the Wiener space is embedded.
This would be a consequence of the smaller effective population size in the human lineage [ 44, 45], where unfavorable mutations would be more likely to replace existing variation and thus contribute to more rapid evolution.
Within a few months she had performed in "Symphonic Variations," and later she stepped in to replace another injured dancer in a televised Christmas performance of "The Nutcracker".
These experiments helped repudiate the last vestiges of the theory of four elements, which Priestley attempted to replace with his own variation of phlogiston theory.
Conversely, the last three slow time scales are sensitive to variations in kinetic parameters and it may be caused by a reducing number of alternative pathways to replace the effects of kinetic variations.
There are many variations on this recipe, and you may decide to replace some seasonings or add your own.
To replace Michael Steele?
He offered to replace them.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com