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A third approach is to use known sequence variation to design a library.
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It would be a mistake to assume that, because natural selection of genetic variation leads to design, that all semblance of design arises solely from natural selection of genetic variation.
But huge amounts of data with variation assist to design effective predictive model.
The ITS-1 region of each Eimeria species had sufficient inter-specific sequence variation enough to design the primer sets that differentially amplified each target species.
However, short periods of historical data or TMY data do not capture enough of the variation required to design a reliable renewable energy system.
Although a high degree of intraspecific homology was observed, interspecific variation was sufficient to design species-specific primers based on sequence of the ITS region.
Indolic substitution and maleimide variations were performed to design a new library of BDCZs and their cytotoxicity were evaluated on two representative cancer cell lines.
Thus, it is vital to understand the variations of suicide patterns over time, space, population groups (age, sex and ethnic groups) and the possible reasons for these variations, in order to design effective suicide control and prevention programmes.
We demonstrate how these estimates of variation can be used to design practical sampling protocols to test other hypotheses.
Price variation allows the government to design contracts with countervailing incentives, potentially eliminating some firms' information advantage.
Future research is needed to identify moderators that explain the variation in effects and to design sexual health interventions for young adolescents.
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