Sentence examples for variation that alters from inspiring English sources
Understanding how genetic variation that alters gene regulation contributes to human traits, including risk for common diseases such as diabetes.
Although correlations between the differentiation capacity of hPSCs and these genetic variations have not been systematically examined, it is feasible that cellular pluripotency and differentiation propensity may differ in different hPSC lines partially due to intrinsic genetic variation that alters cell signaling mediated by protein phosphorylation.
Among the key features critical for a decision support framework in clinical genetic testing is a reliable phenotype classification tool and scoring metric to predict consequences of a variation that alters protein structure.
(For example, it has been noted that little more than a general A + U richness may suffice for function as a plant polyadenylation signal [ 27, 28]. Thus, it is conceivable that modest sequence variation that alters A + U content may be sufficient for the origination of a new polyadenylation signal).
The existence of genetic variations that alter risk of developing both obesity and prostate cancer could constitute evidence in favour of a causal link between the two diseases.
However, variations that alter the protein sequence occur in very few genes.
Single nucleotide polymorphisms (SNPs): genetic variations that alter a single nucleotide in the genome.
Genetic variations that alter this site of action might account for this and other reported cases of local anesthetic "resistance" or failure.
Second, we only considered gene variations that altered the open reading frame of the encoded protein (nonsynonymous amino acid changes, frameshifts, truncations, nonframeshifting indels, splice site alterations and stop codon losses).
Phenotypic variation that is altered by genetic background argues for the presence of genetic modifier loci that can ameliorate or enhance aspects of the dystrophic phenotype.
Mutations create DNA sequence variation that may alter gene function as well as DNA conformation and protein binding [ 1, 2].
