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Here we analyze passenger DNA methylation patterns from opposite sides of 12 primary human colorectal cancers (CRCs) to evaluate whether the variation (pairwise distances between epialleles) is consistent with a single clonal expansion after transformation.
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The R values indicated that no less than 70% of the total variation in pairwise transitions and transversions could be explained by the linear relationship between pairwise distances and the total number of transitions and transversions.
It is first described by Chakrabarti and Gilles [20], which is a variation of pairwise stability.
Brain structures showed variation in pairwise allometric relationships suggesting relative independence among structures in evolutionary changes in size, even when controlling for phylogenetic effects.
To examine rate variation further, pairwise analysis of nonsynonymous (d N ) and synonymous (d S ) substitutions for plastid and nuclear rpl32 homologs was performed.
Although geographic distance among populations explained a significant amount of the variation in pairwise F ST 's in Japan and in non-glaciated North America, the amount of variation explained was low (Fig. 4; 6–20%).
Instead, in a case study of the blotched tiger salamander (Ambystoma; Spear et al. 2005), population-based landscape models explained up to 80% of the variation in pairwise FST.
The interaction between the level of coevolution (20%and25%5%) and the variation of pairwise divergence levels also showed no effect on the detection of true coevolution (F2 = 1.061; P = 0.374).
Since PGP uses AHP ratings as input, the variations of pairwise comparisons in AHP will influence the final order quantity.
We observed that in the absence of P1, flucloxacillin showed significant conformational variations with pairwise RMSDs greater than 8 Å regardless of the scoring function.
We validated this approach using geNorm software, version 3.4, which gave an expression stability measure based on the average pairwise variation of the three genes [ 32].
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