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Intuitively, for two neighboring points in the domain, sudden variation of the cost function with respect to both time delay criteria and attenuation model constraints is unlikely, and hence the resulting cost functions are usually expected to be rather slow varying and well behaved, away from the sensors.
The variation between scenarios was reflected in the variation of the cost per screen detected child which was calculated for each scenario.
The high variation of the cost of TB treatment is caused by the different health care systems, perspectives (i.e., provider and patient), cost components, and methods of calculation and data collection used by the respective researchers.
The adjusted R square of the combined regressions is 0.80, with an F statistic of 509 (p < 0.0001), indicating that the model explains a large part of the variation of the cost per bed-day across countries [ 68].
A cost consequence analysis is a variation of the cost effectiveness approach that provides costs and outcomes (consequences) in disaggregated form, and thus is more transparent than, e.g. an analysis reporting cost per quality-adjusted life-year.
The adjusted R squared is 0.54, with an F statistic of 21.33 (p < 0.0001), indicating that the model explains more than half of the variation of the cost of printed media across countries.
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Only one previous study has examined the extent of genetic variation for the cost of immunological deployment, however in that study costs of immunity could not be distinguished from costs of parasitism [ 25].
The larger the coefficient of variation of the costs, the larger the gain.
In these scenario analyses a strong variation of the cost-effectiveness results was obtained ranging from €23,512 (best case) to €176,958 (worst case) per QALY gained by AVD therapy.
In these analyses a strong variation of the cost-effectiveness results was obtained ranging from €23,512 (best case; RR 100%; AVD first year costs €55,000) to €176,958 (worst case, RR 25%; €115,000) per QALY gained by AVD therapy.
Figure 3 shows the variation of the cost-effectiveness ratio in function of the prevalence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com