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Previous studies have shown a wide variation of reported emission estimates: the results of this study are benchmarked with data from those studies.
Fig. 2 illustrates this wide variation of reported incidence rates.
On the other hand, the within-study variation of reported non-compartment PK parameters is moderate, CV = 27%.
Variation of reported percentages is most likely based on selection of cases (benign and malignant as well as morphologic subtypes), technical factors and subjective interpretation.
For the midazolam/ketoconazole system, a mixed inhibition model coupled with independent binding of the drug, inhibitor, and metabolite is sufficient to explain the variation of reported Vmax, Km, and inhibitor constants across a range of reported studies.
One reason for the variation of reported inhibition types and the values of inhibition constants is that complex cellulase mixtures are often used instead of purified cellulase components in experiments.
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Thirty-six of the 44 studies reported preoperative comorbidities but significant variation of conditions reported prevents meaningful comparison.
TSNP were immobilized on PEM-modified glass substrate by a variation of previously reported layer-by-layer technique [22].
Given the difference between the adjusted and unadjusted results, it is possible that some of the variation of results reported in the broader empirical literature, looking at risk and entrepreneurship, could potentially be related to measurement error.
Additionally, we examine how the study-to-study variation of the reported reliability coefficients can be explained by covariates.
Due to the extreme variation of the reported values we applied two data filters to remove a large proportion of non meaningful results from the final analysis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com