We also describe the conservation and variation of differentiation-related genes predicted from the annotation of K. setae NBRC 14216T genome, as well as the possible coding capacity of the genome for bioactive secondary metabolites.
We identified and rigorously optimized >45 variables that affect the experimental variation of cardiac differentiation in genetically diverse hPSC lines.
Although the reasons for this variation are not certain, one possibility is that it reflects stochastic variation of the differentiation state and subsequent priming of bivalent genes within a population of ESCs.
This variation in amount of differentiation may be due to the wider geographical sampling on the West Coast.
Line-to-line variation in terms of differentiation potential is a common phenomenon in pluripotent stem cell cultures (e.g. see Osafune et al., 2008 ) and in our hands we also observe some variation between different EpiSC lines both in terms of the extent of induction of NMP-like cells upon culture in FGF2/CHIR as well as the timing of their emergence.
B. Group of genes with variation during myogenic differentiation of satellite cells and no variation during C2C12 differentiation.
The possibility of geographic variation in population differentiation of parasitoids is very interesting considering the previously documented parasitoid mediated indirect interactions between G. tenella and G. calmariensis in northern localities.
In addition, it should be interesting to investigate intraspecific variation of sex chromosome differentiation and rearrangements among genetically divergent populations.
These findings show that the VMI gives new information on the mechanism of tumour angiogenesis independently from microvessel quantitation, there is a wide variation in the differentiation of tumour vasculature but the degree of capillary differentiation is not associated with quantitative angiogenesis.
The clusters showed distinctive temporal patterns characterised by their initial levels of abundance and variation during differentiation (Figure 2).
In this paper, we assume that change in PD is proportional to change in niche space or ecological function, meaning that the magnitude of variation in niche differentiation is dependent on the time since divergence (i.e., Brownian trait evolution).
