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However, the efficacy of these immunoprophylactic strategies is often significantly limited by either difficulty in engineering effective vaccines to some respiratory viruses such as respiratory syncytial virus, or because of evasion of acquired immunity as a result of antigenic variation of circulating respiratory viral pathogens (H1N1 swine influenza pandemic, 2009).
The animals were monitored regularly to ensure that they were not stressed thus limiting variation of circulating hormone levels [ 11].
We aimed to determine whether the variation of circulating prolactin concentration associates with diabetes and impaired glucose regulation (IGR) in a cross-sectional study.
The previous studies reported lymphopenia could be affected by various factors including vitamin D deficiency [ 32], weight loss [ 33], variation of circulating metal ions levels [ 34], malnutrition [ 35].
The long-term intraindividual variation of circulating 25(OH D concentrations across seasons has not been well studied and thus is not well understood.
Although 2 main HMPV types are recognized (A and B) (1, 3, 7 ), each with 2 subtypes (A1, A2; B2, B2) (8 ), the extent of genetic variation of circulating HMPV subtypes over time has not been extensively examined.
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The model is validated against experimental data of a similar tunnel in Mathura (India), and is then used to predict the tube-extracted temperature for various parameters such as humidity variations of circulating air, airflow rate and ambient air temperature.
In accordance with animal and experimental data, the absence of significant variations of circulating WBC seen in at-risk drinkers according to the severity of infection is suggestive of reduced immune response in patients chronically exposed to alcohol.
In keeping with this mechanism, we observed that in our nutritional and hormonal, eGHI and STZ mouse models, variations of circulating plasma insulin are closely associated with variation of the hypothalamic COUP-TFII mRNA levels, paralleling the modulation of POMC gene expression and therefore of the melanocortin receptor agonist (αMSH) production.
The proposed advantages of using ARR as a screening method is that this ratio is less influenced by anti-hypertensive medical treatment and the physiological variations of circulating levels of aldosterone and renin [ 21].
An inverse relationship between vitamin D/calcium intakes and breast density has also been observed (Holmes et al. 2001, Berube et al. 2004, 2005, Colangelo et al. 2006), as well as synchronized seasonal variations of circulating 25-hydroxyvitamin D (25(OH D) and breast density (Brisson et al. 2007).
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