Also, based on mutagenesis experiments on other polar pocket residues,31,32 the R150S variation is likely to be a loss-of-function variant.
These issues are especially relevant to pain research where interindividual and interpopulation variation is likely to be high, and where polymorphisms can greatly affect nociceptive sensitivity and susceptibility to pain conditions.
Impaired mitochondrial function resulting from mtDNA and nuclear DNA variation is likely to contribute to an imbalance in cellular energy homeostasis, increased vulnerability to oxidative stress, and an increased rate of cellular senescence and aging.
Some work suggests that moral differences might have similar effects, but it is not yet clear how morality is distributed across the social landscape, and hence where moral variation is likely to occur.
In addition, this variation is likely to reflect noise (e.g., measurement error due to self-reporting).
However, research on heterogeneity effect into traffic flows indicates that co-efficient of variation is likely to deviate under such traffic mostly because of complicated traffic flow dynamics, thereby, making exponential model inappropriate in describing headways.
Notably, this phenotypic variation is likely to be even more dramatic in less managed populations of bees.
However, we do not believe that this variation is likely to have a major impact on the results.
In addition, intraspecific variation is likely to be apparent in Leucocytozoon species of owls, as was shown with L. schoutedeni of chickens, and in other haemosporidians [34], [38].
That such epigenetic regulatory variation exists in recently diverged species suggests a role in reproductive isolation, and that this variation is likely to be adaptive.
The ability of emperors to accommodate changes in patterns of climate and environmental variation is likely to be critically important [3], [40].
