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None of the two aforementioned works, however, studied differences between countries in the variation in the life span per se, since the within-country component of the total variation is simply a sum of variations within single countries and hence does not facilitate comparisons of this statistic across countries.
Number of independent data points for calculation of regular home ranges and the time period during which they were collected varied between individuals because of predation events, variation in the life span of radio collars, length of field season, and dispersal events.
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For many species, senescence in the wild is a deleterious trait with heritable variation, but life spans do not increase, presumably because the reproductive benefits of longer lives would be balanced by costs that decrease reproduction earlier in the life span (Nesse 1988; Austad 2005; Williams et al. 2006).
To test the hypothesis whether fibrates act as agonists of PPARalpha and therefore extent life span in C. elegans, the life span assays were repeated using two strains that lack functional nhr-49, variation ok2165 and variation gk405 (strains RB1716 and VC870, respectively).
Studies attempting to assess the overall genetic influence on variations in the human life span indicated that approximately a quarter of the variation in the adult life spans could be attributed to genetic variation among individuals [ 43].
The variations of the transcriptional activity of HERVs during the life span reported in our study reinforce the assumption that phenotypic differences among individuals hinge not only on epigenetic events [ 44, 46] but also on genetic events [ 16, 54].
The large variation in maximum life span among species points toward genetic factors that specify the mechanisms that protect against aging and disease.
An explanation for differences in neurogenic potential between rodents and lagomorphs could reside in the pronounced variation in life span among these animal species, influencing distinct patterns of growth, maturation, and senescence that may have an impact on the extent and plasticity of neurogenesis throughout life (see [30], [34]).
We collected information about life events and admissions across the life span in 51 bipolar patients.
The reproductive phase is also the life span in which most women need efficient contraception.
Nevertheless, the large variation in maximum life span among mammal species is strongly correlated with rates of senescence in survival [16], justifying its widespread use in comparative studies.
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