To account for variations in the inference due to different initializations, 10 realizations were performed for each inference and the model with the lowest free energy was chosen.
By identifying the causal sites underlying standing genetic variation, the QTN programme provides the opportunity to examine how selection acts on standing variation (and by inference, on variation in the associated traits), thereby connecting theory, quantitative genetics and population genetics.
Variation in inferences about the nature of malaria and helminth interaction among reports could be due to differences in the nature of the study participants (children, pregnant, adults), study design, methodology and the way data was analyzed and interpreted.
The tempting inference then is that variation in the same factor in nature will produce the same phenotypic response – and so plasticity can explain similar environment trait associations in nature.
GLMMs are a very rich class of models that are traditionally used to make such individual-level inference by breaking down the total variation in the observed response into within-subject and between-subject variation.
In instance of considerable variation in data confounding inferences, the data outside of 1 S.D. might have been equilaterally excluded from the data used for statistical analysis.
Almost always, whether in a randomized experiment or a carefully chosen non-experimental setting, causal inference is restricted to a much narrower range of variation in the processes under study than the broader population of interest.
Moreover, there was variation in the definition and methods used for detecting aspiration; these limitations minimize any inferences we can make based on these outcomes.
Motivation: Haplotype inference is an important step for many types of analyses of genetic variation in the human genome.
