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The variation in process parameters reflected changes in crystallinity, optical properties, surface morphology, functional groups and other vital physicochemical properties.
This choice was motivated by the variation in process related market parameters and their impact on profitability.
Furthermore, the proposed input topology makes the device robust in terms of its performance over variation in process, voltage and temperature.
Since variation in process time and process output is commonly accepted to be inevitable for biological processes, application of Process Analytical Technologies PATT) on these processes is challenging.
To achieve this goal, several methods have been used, primarily in screening for enzymes from new sources, enzyme improvement, substrate structure modification, medium engineering, and variation in process parameters.
23 The model emphasises system change and focuses on reducing variation in process performance.
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In the literature, BPS is predominantly conceptualized as the unification or homogenization of process variants (Beimborn et al. 2009), acknowledging local variation in processes as inevitable and necessary (Tregear 2015).
Since polycistronic transcripts are cleaved to generate mRNAs for each mitochondrial gene-derived cistron, the initial molar ratios are equal and subsequent variation in processed transcript quantities result from differences in mRNA stability [64].
To assess variation in processes of care, we used the Index of Qualitative Variation (IQV).
Measuring the process was a prerequisite for becoming aware of variation in processes and implementing measures to eliminate it.
For example, incident reporting, clinical auditing and quality improvement approaches such Statistical Process Control all identify, and aim to resolve, 'defects' or unacceptable variation in processes.
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