Exact(40)
Coverage varies across individuals (averages: vertical dashed lines); in particular, variation in genomic coverage suggests the effect of phylogenetic distance to the reference genome – more distantly related species have fewer RAD loci mapped.
For example, the technology has reached a sufficient level of detection and specificity to allow the evaluation and a detailed analysis of variation in genomic DNA such as SNPs, gene copy number and structural variations.
Thus, there is significant variation in genomic organization of Hox genes even within deuterostomes.
Second, a QTL was inferred by computing a statistic representing the relative contribution of variation in window breeding value compared to variation in genomic breeding value.
This variation in LD may reflect a variation in genomic stability that exists between different CNV subgroups, and the investigation of phenotypic associations with more complex CNV regions or with rare CNVs may require the use of specific detection platforms.
The observed variation in genomic GC content has a strong impact on synonymous codon usage with most of the variation occurring in the third codon position due to the redundancy of the genetic code [5], [6], [7].
Similar(20)
Variations in genomic signatures within prokaryotic genomes is therefore occasionally linked to virulence and pathogenicity islands [14], [21], [26].
Array comparative genomic hybridization (aCGH) is an efficient approach for scanning entire genomes to seek variations in genomic copy number variations, genotyping and medical genetics.
Expression quantitative trait locus (eQTL) analysis combines gene expression and genotyping (i.e. SNP) data to determine if changes in gene expression correlate to variations in genomic sequence.
Further, Kari et al [12] first demonstrated that even slight variations in genomic sequence between some ocular strains of C. trachomatis may have an effect on the pathogenesis of trachoma.
However, patterns of co-variation in genomic feature activity ultimately reflect heterogeneity among biological samples.
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