Sentence examples for variation in exons from inspiring English sources

Genetic variation in exons is constrained by negative selection [10], [18], [19].

Based on previous genetic findings and functional studies in familial CAA, we only examined sequenced variation in exons 16 and 17 of APP.

The HLA-G gene includes 42 alleles at the DNA level, 14 alleles at the protein level, and 2 null alleles based on sequence variation in exons 2 4 (the _1 to _3 domains) [22].

An expanded genomic DNA survey on a smaller region of the gene (600 bp) also showed no consistent SNPs differentiating purple- and white-flowered individuals in the exons or introns, although there was modest variation (3.9% variation in exons and 5.1% variation in introns; Table 2).

A total of 92 tomato lines of the EU-SOL core collection were screened for natural variation in exons 1 5 and introns 2 and 4, based on PCR amplification of three amplicons of the SleIF4E gene (Figure S3) from 20 (12X and 8Y) 2D pools using tagged PCR primers.

We find interesting examples in our data set where alterations of protein signatures are not effected by variation in exons that code for such signatures but rather by variations in upstream exons that shift the reading frame; such an observation has been seen as prevalent in literature [ 42].

Our analysis of the recombination landscape across OPN1LW reveals an unusual haplotype structure associated with amino acid replacement variation in exon 3 that is consistent with gene conversion.

Moreover, the large variation in exon lengths between mouse NAS genes and alternatively spliced human orthologs, as shown in Table 5, may also reflect a combined influence on splicing regulation for different types of exons.

Indeed, balancing selection on the ABS can maintain synonymous sequence variation in exon 2 due to genetic hitchhiking, while recombination causes intron 1 to loose polymorphism by genetic drift.

Variation in exon length is evident, even within individual subfamilies, although variation in exon length is greater between subfamilies [see Additional file 3].

gambiae CPR genes show considerable variation in exon position and length.