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Wildlife managers will benefit from the more complete genomic perspectives offered by advances in genomics technologies, as population-level genetic variation has the potential to be partitioned into categories of neutral variation, putatively adaptive variation, and potentially misleading variation.
Despite genetic variation has the potential to arise new protein functions, spontaneous mutations usually destabilize the native fold.
Somaclonal variation has the potential of generating valuable variants in plant breeding.
Mutation rate variation has the potential to bias evolutionary inference, particularly when rates become much higher than the mean.
This underlying molecular variation has the potential to illuminate the action of selection and drift on phenotypic plasticity (Hodgins-Davis and Townsend 2009).
The results indicate that the use of inter-relationship information of miRNA expression and genomic features such as DNA methylation and copy number variation has the potential to elucidate tumorigenesis processes and improve therapeutic strategies for cancers other than GBM.
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Epigenetic modifications, most importantly DNA methylation and histone variation, have the potential to affect gene expression, and are believed to play a major role in the complex pattern of development and differentiation of multi-cellular organisms.
Increased nucleotide substitution rates, altered selective regimes, and increased structural variation have the potential to lead to rapid local co-evolution of these genomes, leading to an increased likelihood for cytonuclear genetic incompatibilities when crossing between populations.
Moderate amounts of sexually antagonistic variation have the potential to reduce the benefits of sexual selection, but the extent to which it does so depends on the relative amount and intensity of sexually concordant and sex-specific selection on the genomic scale [ 38].
The identification of neuroprotective genes based on naturally occurring allelic variations has the potential to inform the development of drug targets for ischemic stroke treatment.
If detected, such variations have the potential to trace open conduit degassing of magmatic bodies and/or diffusive emissions from volcanic and/or crustal sources.
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