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The variation becomes even greater if pseudogenes are also considered.
In addition, the identification of these sources of variation becomes even more troublesome when reliability is consistently low (or high) across studies.
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The variation became even more noticeable when it came to the sample size used for pretesting (Q2.7b and Q2.7c), ranging from over 1,000 (Board A) to around 20 for every pretest (Board C).
This ffc-induced variation became even smaller as the sample size increased (Additional file 1: Figure S2).
It also shows that Hsp83 is involved in the buffering of deleterious variation in these flies, and that this role becomes even more important under heat stress.
The variation in clinical classification, based on which normative considerations are made, becomes even more relevant to MCI and AD diagnosis when considering performance on memory-specific measures.
Our work shows that Hsp90, a regulator of the stress response and of signaling, helps buffer deleterious variation in fruit flies derived from wild population, and that its buffering role becomes even more important under heat stress.
Having established actors becomes even more critical".
This problem becomes even more complex when one considers that different patients may place a different value on a particular benefit (inter-individual variation) or even the same patient may place a different value on the same benefit (intra-individual variation), depending on the circumstances.
Despite this, the variation in responses was so striking that we expect that with the inclusion of more international experts with more heterogeneous backgrounds this variation would only become even more prominent.
He said climate change, which is already beginning to exacerbate variations in weather patterns - some parched climates may become even drier in the future, wetter ones rainier - makes that task even more pressing.
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