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Exact(17)
Actually, there was only a single amino acid variation at position 537 between AP8 and AP9 (Table 3), implying their tight evolutionary relationship.
However, it would seem unlikely that the variation at position 107 is an exclusive control point in establishing response thresholds among different TCR.
The A and B alleles are best distinguished by a base variation at position 467 and cut with AluI and PvuII respectively [37].
It suggests that T→C variation at position -429 could significantly reduce the transcriptional activity of the RAGE promoter.
The major T-cell epitope Bet v 1142 156 has an amino acid variation at position Thr.
The results suggested that T to C variation at position −429 could significantly reduce the transcriptional activity of RAGE promoter.
Similar(43)
The C-track length variation at positions 16182 and 16183 in HVS-I and the indels at positions 00309 and 00315 in HVS-II were excluded from further analyses (Table S1).
Indeed, the variation at positions 145 and 148 was shown to determine sensor characteristics to a large extent.
Additional variation at positions 264 and 704 does not modify the effect of 37W or 607F on the nuclear abundance of DISC1 (Supplementary Material, Fig. S1).
Amino acid variation at positions 197 and 308 are also known to influence spectral sensitivity, however, all ray-finned fish surveyed to date possess only H197 and A308.
Thus, natural variation at positions 106 and 237 also has no effect on Rx recognition of the "KR" variant of the PVX CP.
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