Sentence examples for variants with higher from inspiring English sources
Initial screens were designed to select for variants with higher trypsin inhibitory activities than the parent after treatment with a reducing agent.
These results provide direct evidence that engineered EGS variants with higher targeting activity in vitro are also more effective in reducing gene expression in animals.
Directed evolution of CrtOx by error-prone PCR resulted in a number of variants with higher activity on C40 carotenoid substrates and improved product profiles.
Additionally, we developed RIVER (RNA-informed variant effect on regulation), a Bayesian statistical model that incorporates expression data to predict a regulatory effect for rare variants with higher accuracy than models using genomic annotations alone.
This process produced E. coli variants with higher whole cell activity than wild-type, which was found to be a consequence of increased protein expression rather than any increase in enzymatic activity.
In total, 9 replicating SNPs were discounted either because nearby variants with higher significance had been selected (n=3), other variants in the gene had previously been tested (n=2) or because the significance level was modest (P meta ≥ 0.01, n=4).
Finally, we applied the strict mask to obtain a set of variants with high accuracy.
He is a member of the International Inflammatory Bowel Diseases Genetics Consortium (IIBDGC) and has co-led its recent fine-mapping effort to resolve known genetic associations to variants with high causal probabilities (Huang et al., Nature, 2017).
All known enterovirus variants with high-level resistance toward capsid-binding molecules have mutations of residues directly involved in the formation of the hydrophobic binding site.
Schizophrenia is a neuropsychological disorder with a strong heritable component; genetic risk for schizophrenia is conferred by both common variants of relatively small effect and rare variants with high penetrance.
Previous Photinus pyralis red-emitting variants with high Km values for ATP have performed disappointingly in live cells despite having much higher relative specific activities than enzymes like Click Beetle Red (CBR).
