Sentence examples for variants with effect from inspiring English sources

Consistent with other genome wide association studies of schizophrenia and bipolar disorder [10], [21], this latter approach was unable to find any significant common variants with effect on either schizophrenia or bipolar disorder.

We exclude common genetic variants with effect sizes above a modest 1.3 odds ratio for a single variant as contributors to genetic susceptibility shared across the partial epilepsies.

In Figures  9, 10, 11, 12, the X axis stands for the sample size when the variants with effect of opposite side are considered.

A major advantage of these methods is that they can appreciate the contribution of variants with effect sizes too small to be picked up through traditional marginal analysis.

Complex traits consist of an unpredictable mix of common, uncommon and rare genetic variants with effect sizes that are inversely related to their frequency.

However, haplotypes can also have smaller effects if they combine QTL allele variants with effects in opposite directions.

It is also possible that rare susceptibility variants with effects independent of or specific to tumour subtypes will be identified.

The discrete nature of the genotype phenotype associations further implies low developmental pleiotropy of the cryptic alleles; variants with effects under one perturbation have no detectable effects under another.

Veridical takes Shannon Pipeline output from predicted genomic variants with effects on splicing and performs a case-control analysis of corresponding expressed transcripts that cover the same genomic region, taken from normal tissues.

More generally, haplotypes of ERCC8, FANCA, FANCC and NBS1 subject to apparent positive selection should represent good candidates for genetic variants with effects on brain size and cognitive capacity in nonclinical human populations.

The finding that the addition of SNPs identified for another trait to the trait-specific SNPs explained an additional portion of heritability (particularly for the QRS SNPs and PR) strongly suggests the presence of variants with effects across these traits.