Sentence examples for variants with both from inspiring English sources

In theory, a family based study design and genome sequencing can embrace the search for rare variants with both high and medium effect size, whether monogenic or oligogenic.

The interactions of bH1 and its variants with both antigens were characterized by large favorable entropy changes whereas the Herceptin/HER2 interaction involved a large favorable enthalpy change.

The Relief algorithms are an excellent candidate for application in the first stage since it is capable of identifying variants with both main and interaction effects.

When considering imbalances at variants with both alleles included in the alignment, precision only varied slightly, but it increased at predicted sites with higher thresholds.

Therefore, here we conducted a systematic comparison between the two tests, using synthetic data, rare and common variants, with both case-control and continuous-valued phenotypes, and under various types of model misspecification.

The full model variants with both p53-deficiency and constitutively active NF-κB (Additional file 1: Table S2, column D) as well as the full model variant with constitutively activative p53-P (Additional file 1: Table S2, column E) enter logical steady states.

HCDiff callings presume at least three reads with the variant with both forward and reverse reads included; alternatively the quality scores at the variable positions must be over 20 (or over 30 if a homopolymer of five or more bases is involved).

In contrast, the model variant with both p53-deficiency and constitutively active NF-κB enters a logical steady state (marked with an ellipse in Figure 4d).

The fixation of the variant with both duplication and gene conversion is therefore likely for wider range of parameters compared with that of the variant with duplication only (see previous section).

A similar observation was made for overexpressed GFP-tagged MVI constructs encoding all four splice variants with the exception of the variant with both inserts (L+S+), which had a higher tendency to localize to the perinuclear area (Fig.  1e).

The M. truncatula Hapmap project gene annotations revealed that the candidate AtNIP5 1 homologue on BAC AC153003 has a potential splice variant, with both gene products (GeneID: Medtr4g006730.1 and Medtr4g006730.2) predicted to encode NIPs.