Sentence examples for variants will provide from inspiring English sources

Identification of these functional variants will provide additional insight into disease pathophysiology and may provide the scientific rationale for the design of more individualized prevention and treatment strategies for obesity and its metabolic complications.

It is highly likely that a model based on a larger number of genetic variants will provide much improved prediction of disease, although theoretical studies suggest that predictive capability that will be of direct clinical utility may not be possible [43].

Moreover, the identification of lineage specific genes and gene variants will provide candidates for future functional studies.

Ultimately, only independent replication of these studies with increased sample size and/or functional validation of the candidate gene allelic variants will provide proof.

For this reason, the most complete exome-sequencing studies will examine individuals from a variety of ancestries with the expectation that segregating variants will provide insights about different (but potentially overlapping) subset of genes in each population.

However, to understand the interconnections of PAs biosynthesis, its catabolism, and conjugation along with PAs signaling aspect a detailed metabolite profiling among allelic variants will provide a framework for unraveling genetic determinants (structural/regulatory) with genomic assisted analyses.

Directly genotyping a 'causal variant' will provide the greatest odds ratio for disease association and provides the rationale for locus-specific sequencing and further association testing.

As such there is a need to find other genes and/or genetic variants, which will provide novel clues to the complex pathogenesis of Huntington's disease.

We then generated a catalog of filtered LoF variants that will provide a resource for future functional studies on economically important traits thereby contributing to the contemporary cattle genomics research.

The improved stability of the variant MLVs will provide more facile virus production and increased transduction efficiency.

The rationale behind studies of genetics in complex diseases is that identification of gene variants contributing to susceptibility will provide important information concerning the pathogenesis and hopes for future therapy.