Sentence examples for variants which result from inspiring English sources

The same gene variants which result in rapid activation of a vigorous inflammatory response to infection may have the disadvantage of increasing the risk of auto-immune and inflammatory diseases later in life [8], [9].

This hypothesis implies that gene variants which result in an increased energy deposition as fat have accumulated over time to maintain reproductive function as long as possible and to enhance survival during famines.

Briefly, successive waves of spirochetemia characteristically seen in relapsing fever are associated with different antigenic variants, which result from rearrangement of silent variable membrane protein genes into an expression locus.

The GPA assay measures stem cell or precursor erythroid cell mutations expressed in peripheral red blood cells of MN heterozygous subjects, identifying NN variants, which result from loss of the GPA M allele and duplication of the N allele, and N phi variants, which arise from gene inactivation.

We searched the following terms: "Exome AND sequencing AND pedigree AND rare AND variants" which resulted in 192 articles of which 29 abstracts were read, 15 were read in full and 14 were included.

We found two independent examples of potent CTL responses generated against epitope variants, which resulted in selection of the subtype B consensus sequence.

Another reason is the variability in the behavior among different tumor variants, which results from the intrinsic heterogeneity of tumor cells (genetic and epigenetic) [16] and the heterogeneous environment in which the cells reside inside the tumor [17] [19].

By amplifying, these elements spread these genes or gene fragments throughout the genome (sometimes as chimeric variants), which results in opportunities for gene duplication and exon shuffling.

This might indicate a very low rate of degron presentation in darkness in these variants, which results in a similar protein turnover rate.

In summary, the majority of osmosensing circuits containing aromatically tuned receptors resulted in increased in signal output as EnvZ-V5 levels increased, with the exception of those containing the WLF-2 or WLF+1 variants, which resulted in decreased signal output.

We further restricted SNPs to those with a minor allele frequency (MAF) of ≥ 10% among controls because of limited power for interaction assessments with rarer variants, which resulted in 394 SNPs.