In conclusion, this study shows that MDP-dependent pathways are inhibited in CD monocytes without the disease associated CARD15 variants, which indicates that the innate immune response is deficient in CD.
Endogenously expressed S100A4 were shown to exist in several charge variants, which indicates the presence of posttranslational modifications altering the net charge of the protein.
Tajima's D is 0 for neutral variation, positive when an excess of rare polymorphism indicates positive selection, and negative with an excess of high-frequency variants, which indicates balanced selection (Tajima 1989).
Three species/subspecies of diploid wheat show a significant negative Tajima's D due to an excess of variants, which indicates that they significantly departure from an equilibrium neutral model.
Comparative genomic analysis of the IL4I1_2 variant was done with help of the UCSC genome browser [ 53], which indicated variant cDNAs from mouse [ 58] (ESTs Acc BY100275, BY099330, BY087056, BY092834, BY088421) and rat (Acc CV117152).
All MLVA types from Spain were single-locus variants of MLVA type B, which indicated this type was the founder genotype of F. tularensis that caused tularemia in northwestern Spain.
We found that the T allele of rs2294008 was significantly associated with a reduced risk of ESCC, which indicated that genetic variants at 8q24 may be implicated with ESCC susceptibility.
We obtained a novel transcript variation of MYCT1 using 5' RACE, named c-Myc target 1 transcript variant 1(GenBank access number GU997693.1), which indicated the transcript start site of MYCT1 and its variation.
An example is given in Figure 3, demonstrating sequenced isomiRs for miR-1, which indicated that the majority of porcine miRNA nucleotide variants resulted from post-transcriptional modifications.
Two of the white variants showed a larger cell size and two showed larger capsules, which indicated phenotypic changes beyond melanin formation.
