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42 variants were mapped on HVL (SprA).
Lastly, 19 variants were mapped on the predicted protein (RS13800) and 92 nt downstream intergenic region.
Variants were mapped to the 3D structures of MDC1 (PDB ID 2AZM 42 and MCPH1 (PDB ID: 3U3Z 43 in complex with phosphorylated histone H2AX.
Four types of variants were mapped onto PDB structures and characterized by their local structural environments (see Datasets S1, S3 and S5).
Variants were mapped to genes using the CGI gene files.
Variants were mapped to GRCh38 by Ensembl (release 76).
Similar(47)
The remaining 17 variants are mapped onto the E. coli SSADH structure (Figure 8, Table 2).
Quite a number of these common variants are mapped to genomic regions without being firmly associated with specific genes.
Variants are mapped onto the best available transcript, using a greedy algorithm (see Supplementary Methods), and those variants that cause missense changes are identified.
Additionally, users can browse the entry by chromosome in a graphical way, in which all the variants are mapped on the chromosomes and linked to gene information page.
Variants are mapped to human reference coordinates (GHCr37.p7) by walking the read overlap graph in both directions until an "anchor" read, where a continuous 65 bp matches the reference, denotes the beginning and end of each variant.
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CEO of Professional Science Editing for Scientists @ prosciediting.com