Further examination of the samples from that study, show that all short DCLK1 variants are induced by BDNF but not the long variants (see figure 1B).
Expression of full-length FE-BRCA2 variants was induced with 2 μg/ml doxycycline for 48 hr prior to analyses.
In flies and plants, when the activity of Hsp90 is reduced via silencing from mutations or treatment with specific inhibitors such as geldanamycin, a wide spectrum of phenotypic variants is induced (Rutherford and Lindquist 1998; Queitsch et al. 2002).
Expression of PTE variants was induced by adding IPTG to a final concentration of 1 mM and cultures were incubated for an additional 2 hr at 30°C or for 1 hr at 37°C in rounds aimed at reducing chaperone dependence.
In rat, we previously demonstrated that the Carp variant is induced by BDNF exposure, but at this time we did not further look at the other transcripts.
The data set shown here was measured when the respective co-expressed Spy variant was induced with 0.1 mM IPTG.
While RCAN1-1 seems to be constitutively expressed in most tissues, transcription of the RCAN1-4 varisnt inducedcedede novo by several stimuli that activate the calcineurin-NFAT pathway (Cano et al, 2005; Crawford et al, 1997; Ermak et al, 2002; Esteban et al, 2011; Minami et al, 2004; Wang et al, 2002; Yang et al, 2000).
This indicates an increase in both retrograde and anterograde protein transport between the ER and the Golgi apparatus that is not observed during induction of the control strain and occurs only to a markedly reduced extent when expression of the I56T lysozyme variant is induced.
A programme checking varietal characteristics of material grown up after a decade of storage in vitro is showing that very few morphological or ploidy variants have been induced (van den Houwe et al., 1995).
In contrast to the constitutively expressed long splice variants HOMER1b/c, the short splice variant HOMER1a is induced by neurotransmission activity as an IEG, acts as endogenous negative modulator of the mGluR/IP3 receptor signaling complex and prevents excessive glutamate-induced neuronal activity [37].
