Sentence examples for variants were engineered from inspiring English sources

NfsB variants were engineered so that each NfsB molecule only has one cysteine group on the enzyme surface.

APC activates cell signaling networks with alterations in gene expression profiles by activating protease activated receptors 1 and 3. To minimize APC-induced bleeding risk, APC variants were engineered to lack > 90% anticoagulant activity but retain normal cell signaling.

To understand the influence of these aromatic amino acids and the associated high hydrophobicity, apoA-I variants were engineered in which aliphatic amino acids were substituted with or without causing a decrease in overall hydrophobicity.

T-cell receptors specific for an immunodominant Gag epitope, SL9, and its escape variants were engineered to achieve supraphysiological affinity and fused to a humanised CD3-specific single chain antibody fragment.

This variant was engineered to combine mutations that enhance MBP solubility and affinity purification, as well as provide crystal-packing interactions for increased crystallizability.

Moreover, the three single amino substitution variants that were engineered in the barley Mlo protein based on the data of powdery mildew resistant Arabidopsis Atmlo2 mutant alleles (S187F, D219N, D251N) also localize to a cytoplasmic loop.

To confirm that these genotypic modifications were consistent with the phenotype expressed by these variants, insertion mutants were engineered by introducing the cat gene, conferring resistance to chloramphenicol, in hpuA and the spectinomycin resistance cassette in hmbR.

In this manner variants of the BBP were engineered which exhibit high affinity and remarkable specificity for haptens like fluorescein and digoxigenin.

In order to explore the role of this quaternary structure, dimeric variants of Escherichia coli DHDPS were engineered and their properties were compared to those of the wild-type tetrameric form.

Two variant clones of each enzyme were engineered to increase protein solubility and to facilitate purification, as reported for CYP2B enzymes from multiple species.

Interleukin-3-dependent hematopoietic cells were engineered to express variant human EPORs using retrovirus-mediated gene transfer.