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Four variants were created.
To diminish the risk of generating a human anti-mouse antibody response in patients, chimeric variants were created.
These three variants were created from practical reasons they enable convenient description of the shape of rasters for calculation.
As an alternative to complete removal of the loop domain, Bcl-xL variants were created in which aspartate residues containing potential caspase recognition sites within the loop domain of Bcl-xL were removed.
Eight variants were created for each object in go trials: 4 colors (blue, yellow, green, red) ×2 positions (in the front or back).
To test the feasibility of the approach, CPY* deletion variants were created systematically to eliminate a potential export signal (Fig. 1A).
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Variants are then tested empirically and further variants are created based upon their performance.
A family of stabilized variants was created including a consensus-driven triple variant, A275P/N186D/V622I.
Based on sequence alignment and structural modeling, a library of enzyme variants was created by a semi-rational evolution strategy in position Thr238 and Pro242.
In the process of AS additional variants are created among the mature mRNA transcripts through modification and rearrangement of exons (e.g. [14], [15]).
To obtain a thorough understanding of substrate specificity of the protease, a substrate library of 19
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CEO of Professional Science Editing for Scientists @ prosciediting.com