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Approximately 3 times as many upstream (24) compared to downstream (7) variants were identified, while 3′-UTR variants were approximately double the number in the 5′-UTR.
The maximal Trp fluorescence emission wavelengths (λmax) of all the ES variants were approximately 318 nm (Fig. 1d), indicating a relatively stable core structure of ES variants.
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The estimated divergence time of black bear DQB variants was approximately 11 ± 4.6 MYA.
To estimate the number of tests that would be performed genome-wide, we assumed that the density of variants is approximately equally distributed across all chromosomes.
Furthermore, the distribution of single base pair mutations in the G1 exome predicted to generate amino acid variants was approximately consistent with previous studies [ 37, 38].
The ratio of dTMRCA to dS in the DQB variants was approximately 3 (dTMRCA = 0.078 ± 0.032, dS = 0.028 ± 0.013), suggesting an effect of population fragmentation.
At high coverage the rate of falsely called variants was approximately 2−3.6 % for SNPs, and 30−39 % for indels depending on the aligner.
The simulation times of the network configurations using the different mutated TetR variants are approximately 4.5 hrs, where the execution times increase slightly as we decrease the binding affinity of TetR for all TetO.
For variants of equal strength, the expected F statistic in the univariate linear regression of the risk factor on one of the variants is approximately the same as the expected F statistic in the multiple regression on all of the variants.
This means that, for example, the use of GMM and SMM methods for Mendelian randomization when BMI is the exposure and the outcome is binary is likely to lead to problems of identification even when the sample size is very large, because R for the Speliotes score, comprising the 32 leading BMI-related variants, is approximately 1.4% in the larger data set used to derive the Speliotes score (33).
It is found that when expressed in this form the exponent of this variant is approximately 2 and, as such, is considerably lower than the exponent in "Paris like" power law representations for delamination growth in composites.
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