Sentence examples for variants we hypothesized from inspiring English sources

Across all variants, we hypothesized that those previously associated with PTSD or other anxiety disorders and/or a relative decrease in 5-HTT expression would predict increased amygdala and ventrolateral PFC activation [ 37, 40, 41, 57, 58].

The apparent positive selection of MTL1 is thus highly interesting, and since the identified variants in this ORF were solely missense variants and not loss-of-function variants (such as stop and frameshift variants) we hypothesize that the CWI sensing in the adapted strain might have undergone functional alterations.

We examined the transcription of 5'UTR variants and we hypothesized that they affect RPS19 protein synthesis rate as a possible contributing mechanism in DBA.

As the c.-540G>A variant disrupts a consensus SP1 transcription factor binding site (GG G GCGGGGC > GG A GCGGGGC) in which there are no other variants reported in dbSNP138, we hypothesized that it might influence PIGY gene expression.

The complete list of mitochondrial unique variants identified is reported in Additional File 2. As previously observed for nuclear variants [ 23- 25], we hypothesized that lymphoblastoid cell lines (LCLs) might have a higher rate of mitochondrial mutations than blood.

We hypothesized that variants in critical genes of chromatin remodeling pathway might contribute to the susceptibility of lung cancer.

We hypothesized that variants in 5 critical splicing factor-associated genes might play an important role in carcinogenesis of lung cancer.

We hypothesized that variants in genes expressed as a consequence of interactions between ovarian cancer cells and the host micro-environment could contribute to cancer susceptibility.

We confirmed that the polymorphic 5'UTR variants are indeed transcribed and we hypothesized that these transcripts affect translational efficiency.

We hypothesized that variants in the PPP3CC catalytic subunit might also predispose to BPAD.

We hypothesized that variants associating with lack of radiographic progression also associate with DMARD-free sustained remission.