Sentence examples for variants was substantially from inspiring English sources
The rate of polymerization of both variants was substantially increased in the presence of mAb5E3, such that the two became almost equivalent in behaviour, as seen in the strikingly similar regression lines.
We show that the approach of FH-CR2 to target C3-opsonins was more efficient in preventing complement activation induced by foreign surfaces, whereas the miniFH variants were substantially more active in controlling complement on PNH erythrocytes.
Nevertheless, tools to accurately assign functional and disease relevance to sequence variants are substantially lacking.
Similarly, the response rates for the other SM variants were substantially higher than those reported by the Mayo investigators.
The relative abundance of each of the other variants is substantially less, delaying their recognition and the development of assays for their analysis.
The imputation performance of the 1000 Genomes reference panel for rare variants is substantially better than that of the HapMap phase II panel.
The frequencies of the c. 1080C>T and c.*543T>C variants were substantially higher in the Czech population whereas the frequency of the c. [833C; 844_845ins68] double mutation was considerably lower than in Africans.
The back invasion was possible only when the copy number of the invading variant was substantially smaller.
Aggressive oral vaccination programs in the region eliminated the domestic dog coyote RV variant by 2004, while circulation of the Texas gray fox variant was substantially constrained (18 ).
They found that this variant is substantially compromised in its catalytic efficiency (ca. 850-fold) due to weaker binding of the substrate and decreased catalytic activity.
As the MAF of the FTO variant is substantially lower in Asians (East Asians, ∼17%; South Asians, ∼32%) than in white Europeans (∼45%), and as the effect of this allele on obesity-related traits is similar or somewhat lower in Asians than in white Europeans, the overall contribution of genetic variation in FTO to obesity susceptibility will be lower in Asians, in particular East Asians.
