A brief background of the motivation behind the creation of the above variants is provided.
An overview and critical evaluation of the h-index and its variants are provided by Froghi et al.
The nomenclature and short description of the recombinant NYVAC variants is provided in table 1. Virological and pathogenic characterization of these vectors in cultured cells and in mice is described (Kibler et al., submitted for publication).
The APEX microarray (Asper Biotech) includes 198 mutations selected from six nuclear genes (GJB2, GJB6, GJB3, GJA1, SLC26A4 and SLC26A5) and two mitochondrial genes (MTRNR1 and MTTS1); a detailed list of sequence variants is provided in Table S1.
IGV screenshots for these variants are provided within Figure 6.
The literature references and accession numbers for previously reported splice variants are provided.
An overview of allelic and protein variants is provided in previously published reviews [ 12, 47].
Steady-state kinetic parameters for all variants are provided in Supplementary file 2A.
A detailed scoring matrix for the missense variants is provided in Supplementary Table S3.
A review of harmony search algorithms and its variants is provided by Siddique and Adeli [ 34].
