Exact(6)
A family of stabilized variants was created including a consensus-driven triple variant, A275P/N186D/V622I.
Based on sequence alignment and structural modeling, a library of enzyme variants was created by a semi-rational evolution strategy in position Thr238 and Pro242.
To obtain a thorough understanding of substrate specificity of the protease, a substrate library of 19
A library of 2400 KDPG-aldolase variants was created using ep-PCR with 2 3 base changes per gene.
A filtered list of variants was created for quality score determination similar to the dual approach of Chia et al. [ 18].
This list of variants was created by integrating 14 different datasets from five different sequencers, and it allows us to validate any list of variants generated by our exome analysis pipelines [ 7].
Similar(54)
Four variants were created.
Variants are then tested empirically and further variants are created based upon their performance.
To diminish the risk of generating a human anti-mouse antibody response in patients, chimeric variants were created.
These three variants were created from practical reasons they enable convenient description of the shape of rasters for calculation.
As an alternative to complete removal of the loop domain, Bcl-xL variants were created in which aspartate residues containing potential caspase recognition sites within the loop domain of Bcl-xL were removed.
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