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Furthermore, those different variants unique to GXG-5 probably resulted in the glutamate dependent difference between GXA-28 and GXG-5.
A group of variants unique to the Hadza spanned the DNA encoding for a cannabinoid receptor, a cell surface protein that responds to tetrahydrocannabinol the active ingredient in marijuana which is intriguing because Tishkoff's team observed that the Hadza smoke large amounts of marijuana.
Variants unique to mutant strains were identified using Select Variants (Depristo et al. 2011).
In the third strategy, all the variants unique to a given isolate were excluded.
De novo assemblies received the highest Z-scores, since these may contain structural variants unique to the target genome.
The Haitian and Dominican Republic isolates form a tight cluster, with only four variants unique to individual isolates.
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By then, researchers were closer to identifying the cause — a genetic variant unique to her Ashkenazi Jewish family.
By restricting our analysis to Amish cohorts, we may have identified a variant unique to this population.
In addition to the Tyr cWTSI deletion, only one other validated structural variant unique to C57BL/6N- Tyr cWTSI was localized to chromosome 7; a 233bp homozygous insertion that fell within an intron of Leng8.
Third, the reported effect might be confined to populations of European descent, e.g., if rs11212617 tags a low-frequency variant unique to white populations, further diminishing statistical power in the DPP multiethnic cohort.
We find that while RNA polymerase localized to promoter sequences as expected, single-molecule studies of nucleosome positioning yielded counterintuitive results: a noncanonical histone variant unique to centromeres did not alter binding distributions, whereas addition of a nonhistone protein did.
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