Sentence examples for variants under the from inspiring English sources
A second and more sophisticated approach collects a set of alternative variants under the common label of regime-dependent or state-dependent Vector Error Correction Models (VECM).
Configural invariance, however, necessarily implies a multi-dimensional model, so sum-scores are never sufficient statistics (see Study 1), and the power to detect genetic variants under the sum-score model is always lower than the power under the true latent factor model.
Our goal is to describe the fate of splicing variants under the action of selection once they have appeared in a large population, and to monitor the fitness of the population as a function of allele frequencies, splicing variant fitness and expression levels.
We expressed all nine variants under the endogenous rab7 regulatory elements using the rab7 Gal4-knock-in in heterozygotes.
Minigenes are optimal approaches to test variants under the splicing viewpoint without the need of patient samples.
We compared non-targeted and endoplasmic reticulum- (ER-) targeted variants under the control of a constitutive promoter in identical DNA vector backbones.
Clearly, control transfected cells, that did not express CEACAM1 on their surface, were not able to internalize any of the bacterial variants under these conditions demonstrating that uptake of Opa protein-negative meningococci occurs only in the presence of CEACAM1.
This is not unexpected since the distribution of causal allele frequencies will be more skewed to the rarest variants under this model, which we anticipate to be most difficult to impute, irrespective of the size of the reference panel.
Cocrystallization was also carried out for the other variants under these conditions, but no crystals were obtained.
The fate of a new variant under the influence of selection alone can thus be predicted by evaluating the slope of the fitness landscape at p = 0.
To try to understand the effects of the R438W substitution we crystallized the 39 kDa domain of the W438 variant under the same conditions already reported for the R438.
