Sentence examples for variants to test from inspiring English sources

For example, the McDonald-Kreitman test [10], which uses contrasts of polymorphic and fixed variants to test the neutral model of molecular evolution, requires no knowledge of protein structure or specific functions of residues or domains.

The bow-tie maze offers many procedural variants to test different aspects of memory.

We recently started LOH analysis for several variants to test the presumed association with the BRCA loci.

The AF16::HK104 RILs were genotyped for these variants to test Cb-egl-5 for association with ray pattern variation [see Additional File 1].

The use of Mendelian randomization that uses genetic variants to test for a causal role of urate on renal function was described.

Therefore, future deep resequencing of these regions might help to identify rare variants to test this hypothesis, and we also need to perform the SNP-expression association analysis using lung cancer tissue samples.

The weak [PSI+] phenotypes of some strains (e.g. A4) could be caused by weakened propagation of the same prion variant or by the formation of a different prion variant To test the possibility that different, structurally distinct, prion variants are generated in the presence of different Hsp70 orthologs, we focused on A1 and A4 that have normal and weak prion phenotypes, respectively (Figure 5A).

This SNP is therefore a novel candidate risk variant to test for association with gout in South East Asian populations (ancestrally related to Polynesian).

We inspected the sequencing reads of this variant to test whether the deleterious allele was skewed towards homozygosity and found that of the sequencing reads overlapping this variant position, 46 supported the alternate alleles, whereas only 28 supported the reference allele, suggesting that the alternate allele is homozygous in the mosaic cell line.

In this study we compare the ability of resveratrol and EGCG to inhibit IAPP amyloid formation, examine the interaction of resveratrol with a series of IAPP variants designed to test the role of the aromatic residues and the possible role of Arg-11, His-18, and the N-terminal disulfide-bridged loop, and critically examine the ability of resveratrol to remodel preformed amyloid fibrils.

Nevertheless, RNA variants designed to test the effects of non-A-form structures, helix-perturbing structural elements, and extensions of stable base-paired sequences at either end on recognition by JAZ ZF34 show similar affinities to duplex I (C50 ≈ 500 nM).