Sentence examples for variants to predict from inspiring English sources

The clinical utility of variants to predict individual disease risk of disease is currently limited, but this may change as more variants are identified.

In this study, we tested the possibility of repurposing computational methods of diagnosing disease variants to predict nsSNVs associated with drug-responses.

Thus, with the treatment regimens used in this study, we are unable to confirm the utility of the MIPI and its variants to predict outcome.

In this review, we summarize the current evidence on the role of genetic variants to predict type 2 diabetes above and beyond nongenetic factors and discuss the limitations and future potential of genetic studies.

This review will give an overview of the current knowledge of prostate cancer genetics, with a special focus on the ability of genetic variants to predict more aggressive forms.

Testing BRCA1 and 2 gene variants to predict inherited risk of breast and ovarian cancer has been particularly controversial, with overwhelmingly negative press coverage, except in Utah, home to Myriad Genetics, the company with exclusive rights to perform diagnostic testing [ 5].

The Skippy algorithm (Woolfe et al., 2010) analyzes the genomic region surrounding the variant to predict severe effects on gene function through disruption of splicing.

Genotypic detection of such variants allows to predict their clinical phenotype.

None of these variants appeared to predict quantitative iris color (Table 1).

To filter variants according to predicted pathogenicity, a variant score was calculated for each variant.

Frameshift variants, missense variants, or variants predicted to affect splicing were further screened by DHPLC in 93 controls.