Sentence examples for variants to phenotype from inspiring English sources

Our method has the advantage of improve interpretability of the fitted coefficients relating genetic variants to phenotype.

The likelihood approach provides a natural framework for incorporating the uncertainty in genotype calls into statistical tests relating common and rare variants to phenotype.

This and other next-generation platforms redefine the quest for high-density marker discovery and genotyping, presenting an opportunity for obtaining a high resolution view of the genome to comprehensively link various types of allelic variants to phenotypes.

Determination of the pathogenicity of structural variants is still an evolving area, and so the contribution of structural variants to phenotypes may be overestimated or underestimated (Craddock et al., 2010; Vermeesch et al., 2011), including those structural variants found in individuals with epilepsy (Striano et al., 2012).

The effort performed highlighted varieties relationships and important variants in fruit key processes useful to dissect the path from sequence variant to phenotype.

Collectively, sequence and fine annotation analysis performed can be useful to examine the path from sequence variant to phenotype for improving the utility of the tomato as a model for fruit quality.

This strategy infers and interprets genetic interaction data in terms of quantitative variant-to-variant and variant-to-phenotype influences, rather than non-directional epistasis.

This increased activity forces us to consider how to analyze the data, and we propose the creation of a triple-global database: global first to include all human populations, global second to include the entire genome, and global third to include the most complete understanding possible of variant-to-phenotype relationships.

Nevertheless, the contribution of mtDNA length variants to the phenotype was difficult to determine in this family because they were located in noncoding regions.

Investigating the joint effects of multiple loci by mapping sets of genetic variants to the phenotype has the potential to help explain part of this missing heritability (Marchini et al., 2005).

The information provided by these projects link associated variants to a phenotype via an understanding of the biological basis of these associations in terms of disease pathology and ultimately identify causal genes.