Sentence examples for variants to generate from inspiring English sources

The effective transmission error of the planetary set is calculated using the proprietary transmission software, RomaxDesigner, for a range of design variants to generate a training set of data.

Binding loop mapping of yeast-surface-displayed KD mutants identified high-affinity target binding loops in LCR2, which were then grafted into conformationally compatible loops located on the opposite side of LCR1 within the same or different KD variants to generate bivalent/bispecific KD variants against DR4 and/or DR5 with improved affinity.

In addition, endophenotype research can benefit from successful molecular genetic studies of psychopathology by examining the degree to which these verified psychopathology-relevant variants are also associated with an endophenotype, and by using knowledge about the functional significance of these variants to generate new endophenotypes.

For this reason, one of the major tasks of the HapMap project is to identify all common and rare variants to generate a comprehensive catalog of human genome variations (Altshuler et al. 2010).

Our design strategy relied on a combination of preexisting data from kinetic and structural studies of native kinases, as well as two small, focused libraries of kinase variants to generate an in silico model for assessing the effects of single amino acid changes on favorable activation of l-nucleosides over their corresponding d-enantiomers.

If BQSR is not appropriate, the user first uses the initial informed pipeline in which VQSR is performed on the raw variants to generate a temporary sensitive variant resource which is used during the execution of the informed pipeline that immediately follows the initial informed pipeline.

One channel of an Illumina Genome Analyzer II flow cell was used per variant to generate sequence coverage of approximately 200-500X across the genome.

Human TC10 constructs were obtained from Dr. J. Marshall (Brown University), and then subcloned into the pSP2 vector, containing a CMV promoter and Venus tag (a brighter and more photostable YFP variant) to generate fusion proteins.

When the standard free energy of binding determined from the Kd of the lead peptide, TNF1, is added to the sum of the relative free energies of the individual point-variants required to generate TNF1-opt, a predicted Kd of 1.9 0.7 µM is obtained (Table 2).

Pilon v1.5 (http://www.broadinstitute.org/software/pilon/) was run in variant discovery to generate a list of single-nucleotide polymorphisms (SNPs) and insertions and deletions.

In comparison to the new identified mouse transcript variants, both human transcript variants are predicted to generate truncated proteins.